--- title: The Best Medical Compliance Software Of 2026 image: https://www.selecthub.com/wp-content/uploads/2018/07/Kareo.jpg --- # The Best Medical Compliance Software Of 2026 Last Reviewed: March 9, 2026 15 min read [No comments](https://www.selecthub.com/medical/practice-management-software-compliance/?noamp=mobile#respond) [ ![Bergen Adair](https://secure.gravatar.com/avatar/b9985f5202fbae2efa5a566d409354bbe99c18f8fd579991494c86a2c184dc2b?s=96&d=mm&r=g) ](https://www.selecthub.com/author/bergen/) [Written by Bergen Adair](https://www.selecthub.com/author/bergen/) Technical Content Writer [ ![Kim O'Shaughnessy](https://secure.gravatar.com/avatar/aa3a61ac7e38580003de0d2fb4e71e8281ec6d7b9d0266351a38b2459e313e82?s=96&d=mm&r=g) ](https://www.selecthub.com/author/kim-oshaughnessy/) [Edited by Kim O'Shaughnessy](https://www.selecthub.com/author/kim-oshaughnessy/) Content Editor [ ![Sagardeep Roy](https://www.selecthub.com/wp-content/uploads/2025/01/Sagardeep-Roy-96x96.jpg) ](https://www.selecthub.com/author/sagardeep-roy/) [Technical Research by Sagardeep Roy](https://www.selecthub.com/author/sagardeep-roy/) Senior Analyst Table of Contents * [Best Medical Compliance Software](#Best%5FMedical%5FCompliance%5FSoftware "Best Medical Compliance Software") * [Kareo Billing](#Kareo%5FBilling "Kareo Billing") * [NextGen Office](#NextGen%5FOffice "NextGen Office") * [Centricity EMR](#Centricity%5FEMR "Centricity EMR") * [CureMD](#CureMD "CureMD") * [NueMD](#NueMD "NueMD") * [AdvancedMD](#AdvancedMD "AdvancedMD") * [eClinicalWorks](#eClinicalWorks "eClinicalWorks") * [athenaCollector](#athenaCollector "athenaCollector") * [Final Thoughts](#Final%5FThoughts "Final Thoughts") The Health Insurance Portability and Accountability Act (HIPAA) sets the standard for sensitive patient data protection. Companies that deal with protected health information (PHI) must have physical, network and process security measures in place — and follow them — to ensure [HIPAA Compliance](https://www.hhs.gov/hipaa/for-professionals/privacy/laws-regulations/index.html). Basically, anyone who deals with information regarding patient health has to meet the security standards put forth by [HIPAA](https://www.hipaajournal.com/hipaa-compliance-for-medical-software-applications/). Some medical compliance software — as part of [practice management solutions](https://www.selecthub.com/medical-practice-management-software/) — are better at fully complying with some or all of these medical compliance standards than others. We compiled a list of medical compliance systems highest-rated specifically for compliance features. Never worry about your patient data when you utilize one of these platforms in your medical practice! [Compare Top Practice Management Software Leaders](https://pmo.selecthub.com/top-practice-management-software-site-vers/) ![Best Medical Compliance Software]() ## Best Medical Compliance Software ### [Kareo Billing](https://www.selecthub.com/medical-billing-software/kareo-billing/) ![Score of 94]() Kareo includes robust functionality that can have a positive effect on how a practice works from day to day. This solution allows users to work with ICD-10 diagnostic codes (ICD refers to the International Classification of Diseases, the 10th revision of which was released in 1993.) Users can also work with other identifiers to triage claims and work with contractual agreements with insurance companies to provide a comprehensive medical billing service. This PM medical billing software automates many aspects of the revenue process that are often burdensome for a small practice. It’s designed for small to mid-sized practices and is invested in their clients’ comfort and success with the system. Kareo assigns a success coach to every user for the first 90 days. Users can get in direct touch with a coach to resolve questions and concerns. Kareo’s systems are compliant with HIPAA to ensure the privacy of patients’ information. It’s also ICD-10 compliant and helps users code data sets accurately to ensure accurate transfer of information. The electronic claims transmission feature is used to send insurer-specific and electronic claims swiftly. Kareo’s commitment to security includes providing its services on a highly-secure and controlled platform in company-owned data centers. Kareo does this by implementing best practice security frameworks using both in-house and third-party tools and services. It also obtains industry certifications and independent third-party attestations. Some other security features Kareo implements are third-party audits, external threat assessments by outside agencies, administrative safeguards, data encryption, strict expectations for data handling and secure networking measures. This medical compliance system ensures that users keep all patient records safe and sound. ![Kareo's PM Interface]() Kareo’s PM offers an intuitive interface to streamline patient care **Price:** **$**$$$$ **Deployment:** **Platform:** **Company Size Suitability:** **S** M L ### [NextGen Office](https://www.selecthub.com/medical-practice-management-software/nextgen-office/) ![Score of 91]() NextGen Office provides a centralized patient database that allows users to access patient records from their desktop, tablet or smartphone. The solution records patient demographic and social history information in an easy-to-access database. Medical professionals can import patients’ Rx medication history from SureScripts. This allows them to perform advanced checks for drug interaction and allergies and assists in determining adequate dosage limits. NextGen Office’s YourHealthFile Patient Portal helps users manage workflow by allowing patients to book appointments, to view lab test results, to receive billing updates and to communicate securely with providers. NextGen Office ensures effective communication through automated texts and emails. The solution offers an e-prescribing module that includes a prescription renewal process. It also provides interactive maps to guide patients to the closest pharmacy. NextGen Office supports iPhone/iPad e-prescription and allows users to directly fax to clinic’s document repository. The medical compliance solution offers HIPAA compliant internal messaging system for collaboration between patient, staff, providers, and billers. ![NextGen Office Dashboard]() NextGen Office provides an easy-to-use dashboard to manage patient care NextGen Office has proven ICD-10 success. Their first pass payer rates have not decreased since October 1 and the ICD-10 transition went seamlessly. NextGen Office is HIPPA compliant and ICD-10 ready and also meets ANSI 5010 requirements. **Price:** **$$$$$** **Deployment:** **Platform:** **Company Size Suitability:** **S M L** ### [Centricity EMR](https://www.selecthub.com/emr-software/centricity-emr/) ![Score of 90]() Centricity EMR is a fully integrated electronic medical record (EMR) and practice management solution used by physicians and administrative staff to increase a clinic’s operating efficiency. Both the practice management and EMR modules can be configured to operate as standalone solutions and have built-in tools that let them connect to virtually any hospital EMR or revenue cycle system. This PM solution provides a web portal for your patients. Through this portal, patients can send messages directly to physicians and staff through a secured, HIPAA-compliant network. They can also request appointments and access financial information, such as billing. It is a very secure medical compliance application for capturing and storing patient and medical institution records and sharing them with other stakeholders. Centricity EMR and GE Healthcare are committed to providing their customers with the necessary software upgrades to support ANSI X12 5010 version EDI transactions in time to meet the Centers for Medicare and Medicaid Services’ (CMS) final published compliance dates. Centricity EMR meets the current ANSI X12 5010 requirements. [Compare Top Practice Management Software Leaders](https://pmo.selecthub.com/top-practice-management-software-site-vers/) Centricity’s hosting manages all HIPAA compliance requirements at their end, so you don’t have to worry about the security of your data. To support a secure concurrent user model, Centricity stores all user and resource information in Microsoft Windows 2000 Active Directory, which manages permissions for logon to a computer or network. This application takes advantage of Active Directory security and flexibility. It allows users to manage security for all applications, whether from GE or not, from a single network administrative point. Active Directory validates user information such as passwords and security policies rather than requiring the user to store both network and database passwords. Centricity EMR is ICD-10 and Meaningful Use compliant. It also meets HIPAA 5010 requirements. It uses algorithms or a rules-engine to search across ICD-10 codes for efficient medical coding operations to ensure accuracy and search efficiency. ![Centricity EMR Interface]() Centricity EMR has a secure and simple interface **Price:** **$$$$$** **Deployment:** **Platform:** **Company Size Suitability:** **S M L** ### [CureMD](https://www.selecthub.com/emr-software/curemd/) ![Score of 89]() CureMD provides an electronic health record (EHR) solution combined with practice management and billing services. CureMD’s all-in-one platform appeals to practices of all specialties and works best for mid-sized to enterprise practices. With integrated and interoperable EMR software, CureMD allows a practice to focus on health record management and explore how that promotes enhanced patient care. With models for medical billing services, practice management and population health, the CureMD system with EHR software functionality also provides mobile capabilities in order to help healthcare offices find new ways of capturing and presenting patient information. This EHR employs advanced security features and backup systems that prevent data loss while keeping your information secure, private and accessible. CureMD has several specific features which help you manage the security and confidentiality of your information, including provider passwords, locked screens, access restrictions and audit trails. Administrators can utilize permissions-based features in the application settings, allowing hierarchical access to sensitive data. CureMD is ICD-10 ready and HIPAA, HCPCS and CPT compliant. This medical compliance solution is also compliant with ANSI 5010 requirements. ANSI 5010 is the most recent update to HIPAA compliance. If users are looking for a surefire way to safely house health record data, CureMD is a good option. ![CureMD's Secure Portal]() Safely store images and other files with CureMD’s secure portal **Price:** **$$$**$$ **Deployment:** **Platform:** **Company Size Suitability**:**S M L** ### [NueMD](https://www.selecthub.com/ehr-software/nuemd/) ![Score of 88]() NueMD can help a practice deal with revenue cycles, build efficient internal practices and more. This medical practice management software works independently as a part of an office’s IT infrastructure. It streamlines operations with a web-based medical billing model, allowing doctors and administrators a free hand for other kinds of work. Delivered over a secure internet connection, this software operates independently of the web browser and avoids many security risks that its browser-based competitors face. Data security will never be an issue with NueMD — it is ICD-10 compliant, HIPAA-compliant and prepared for the ICD-10 transition. There is also a HIPAA-compliant mobile app for both Apple and Android devices. One of NueMD’s best features is a personalized assessment of your office. Before clients agree to use the service, the company will do a full assessment of your practice free of charge. The assessment evaluates your finances, technology, workflow and other factors that can affect your practice. It then creates a plan to meet the specific needs of your practice to improve operations and properly implement your new software. With this medical billing company, you won’t receive a general plan that it offers to everyone, but a customized strategy to best benefit your practice. In short, NueMD offers secure, HIPAA-compliant access to software that simplifies administrative work and streamlines the patient care cycle. NueMD publishes a [variety of content](https://www.nuemd.com/webinar/hipaa-and-your-practice-steps-to-compliance) to help other practices achieve medical compliance and is looked to as an industry standard. It is owned by AdvancedMD, whose security protocols are detailed in the next section. ![NueMD Dashboard]() Never lose information again with NueMD’s intuitive dashboards **Price:** **$**$$$$ **Deployment:** **Platform:** **Company Size Suitability**: **S M** L ### [AdvancedMD](https://www.selecthub.com/medical-practice-management-software/advancedmd/) ![Score of 86]() AdvancedMD features all the tools you need to manage your A/R and claims processes in one convenient database. The robust clearinghouse automates manual processes, auto-generated worklists improve productivity and expedite reimbursements, and automatic claims scrubbing gets you an almost 100 percent first-pass claim acceptance rate. AdvancedMD offers the control practices want and need through access to information and charts electronically. AdvancedPM provides automated updates to meet ICD-10, HIPAA compliance and Meaningful Use regulations. AdvancedMD is 2014 Edition compliant and has been certified by an ONC-ACB in accordance with the applicable certification criteria adopted by the Secretary of the U.S. Department of Health and Human Services. As a cloud technology, AdvancedMD is an all-inclusive product and service. In agreement to the AdvancedMD terms of service, the user pays a monthly service fee for a comprehensive product. This certified product version requires a monthly service fee that enables e-Prescribing, computerized provider order entry, formulary checking, interaction checking, VDT (view/download/transmit), clinical information reconciliation, transmit transitions of care, patient education and secure messaging. AdvancedMD is also a vendor of several medical compliance software solutions including HCSI and Compliancy Group. Users won’t need to worry about patient data when it’s stored in the AdvancedBilling databases. ![AdvancedMD Direct Secure Messaging]() Utilize direct secure messaging and access patient files in the same screen with AdvancedMD **Price:** **$$**$$$ **Deployment:** **Platform:** **Company Size Suitability**: **S M L** ### [eClinicalWorks](https://www.selecthub.com/emr-software/eclinicalworks/) ![Score of 85]() eClinicalWorks is certified by the ONC and compliant with EHR technology certification. This is important in assisting practices with meeting meaningful use requirements for stage one and two, generally promoting the kinds of uses desired by government regulators in the age of digital healthcare. This versatile electronic medical record software tool helps medical provider offices streamline clinical workflows and work efficiently in a high-stakes, high-pressure field. The eClinicalWorks is made to accomplish key objectives in healthcare: its cloud-based EHR design assures doctors and others of competent medical billing procedures, a good interconnected EHR system, and great communications and interoperability for architectures. A new feature to the updated version of eClinicalWorks is the medical assistant known as Eva, a smart, voice-activated tool that can recall patient histories, bring up outstanding balances and note comparisons, to name just a few tasks it performs. Eva is said to adapt to providers’ specific workflows as the program gets to know their preferences. This is one of the few EMRs that offers an assistant tool like this, which distinguishes eClinicalWorks from other applications. [Compare Top Practice Management Software Leaders](https://pmo.selecthub.com/top-practice-management-software-site-vers/) If you are switching over from a previous system, the company offers free conversion of your pre-existing data into the new system. The PM from eClinicalWorks supports ICD-10 coding with a tool that cross-supports ICD-9 codes. For ICD-9 codes that translate into multiple ICD-10 codes, the software displays all related ICD-10 codes, which you then select. For practices looking to integrate into the ICD-10 standard, this extra feature saves time and ensures proper charting and reimbursement. The solution enables patients to use HIPAA-compliant messaging to send communication directly to staff or physicians. This medical compliance system is compliant with ANSI 5010 requirements and is also certified by an ONC-ATCB board for meaningful use attestation for stage 1 or stage 2\. With eClinicalWorks, it’s easy to meet documentation standards so you can comply with federal regulations. The software is web-based, so you don’t have to maintain expensive hardware. ![eClinicalWorks Patient Information]() Store patient information securely and accessibly with eClinicalWorks **Price:** **$$$**$$ **Deployment:** **Platform:** **Company Size Suitability**:**S M L** ### [athenaCollector](https://www.selecthub.com/medical-practice-management-software/athenacollector/) ![Score of 82]() With athenaCollector, clients have access to a network of over 75,000 providers, a continuously updated rules engine and back-office teams working on your behalf. Their experts take on your most time-consuming tasks, like claim submission and follow-up, denial management, payment posting, and more, getting practices paid six percent more and 32 percent faster. This system from athenahealth provides cloud-based services for electronic health records, revenue cycle management, medical billing, patient engagement, care coordination and population health management, as well as Epocrates and other point-of-care mobile apps. The platform from athenaCollector automatically updates its databases with the latest and most up-to-date industry standards such as ICD-10 and ensures regulatory medical compliance. The solution is fully compliant with HIPAA 5010 requirements and keeps private data safe from prying eyes. This application also offers secure cloud-based software and flexible support and consultation. This medical billing service provides help and features you can’t find from many medical billing solutions. Users can be confident in the safety of their data — athenaCollector is certified for FIPS 140-2, HITRUST and DirectTrust, PCI data security standards, SOC1/SSAE16/ISAE 3402 and SOC2\. Data is encrypted at rest HTTPS and accessed via multi-factor authentication processes. Data is backed up in multiple locations to prevent data loss. ![athenaCollector]() Use convenient drop-down diagnoses menus with the PM from athenaCollector **Price:** **$$$**$$ **Deployment:** **Platform:** **Company Size Suitability**:**S M L** **Analyst Recommended Related Content** [**Comparison Report:** An Interactive analyst report with comparison ratings, reviews and pricing](https://pmo.selecthub.com/top-practice-management-software-site-vers/?category%5Fslug=medical-practice-management-software&product%5Fslug&slug=medical-practice-management-software&origin%5Furl=https%3A%2F%2Fselecthub.com%2Fmedical-practice-management-software%2F&category=Medical%20Practice%20Management%20Software&scorecard%5Fid=459) ## Final Thoughts Each of these medical compliance software applications comes with its own pros and cons, so make sure to check out our [leaderboard](https://pmo.selecthub.com/top-practice-management-software-site-vers/?category%5Fslug=medical-practice-management-software&product%5Fslug&slug=medical-practice-management-software&origin%5Furl=https%3A%2F%2Fselecthub.com%2Fmedical-practice-management-software%2F&category=Medical%20Practice%20Management%20Software&scorecard%5Fid=459) to review the other features they offer. 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Contributions from Bergen Adair, Sagardeep Roy, Akshay Parekh, and Kim O'Shaughnessy. ## About the Contributors The following team members helped research, create, and review this content. [ ](https://www.selecthub.com/author/bergen/) Written by [Bergen Adair](https://www.selecthub.com/author/bergen/) Technical Content Writer Bergen Adair is a Market Analyst at SelectHub who writes content on CMMS, EAM, facility management and business analytics. She has had a love of the written word since she started reading voraciously at three years old, and studied creative writing at Colorado State University and Swansea University. In her free time she's usually reading (or napping) in a hammock, hiking with her dog, or listening to horror and true crime podcasts. [See Full Bio](https://www.selecthub.com/author/bergen/) [ ](https://www.selecthub.com/author/sagardeep-roy/) Technical Research by [Sagardeep Roy](https://www.selecthub.com/author/sagardeep-roy/) Senior Analyst Sagardeep is a Senior Research Analyst at SelectHub, specializing in diverse technical categories. His expertise spans Business Intelligence, Analytics, Big Data, ETL, Cybersecurity, artificial intelligence and machine learning, with additional proficiency in EHR and Medical Billing. Holding a Master of Technology in Data Science from Amity University, Noida, and a Bachelor of Technology in Computer Science from West Bengal University of Technology, his experience across technology, healthcare, and market research extends back to 2016\. As a certified Data Science and Business Analytics professional, he approaches complex projects with a results-oriented mindset, prioritizing individual excellence and collaborative success. [See Full Bio](https://www.selecthub.com/author/sagardeep-roy/) [ ](https://www.selecthub.com/author/akshay-parekh/) Technical Research by [Akshay Parekh](https://www.selecthub.com/author/akshay-parekh/) Principal Analyst Akshay is a highly analytical and detail-oriented Software Research Analyst with a proven track record of generating industry-standard templates for RTs, RFIs, pricing guides, LTSRs, and more across software categories like Big Data Analytics, BI, ETL, EDI, EHR, Endpoint Security and Medical Billing. He holds a Bachelor of Technology in Computer Science Engineering and an MBA in Marketing and Analytics from IBS Hyderabad. He loves to spend time exploring spirituality, reading books, and watching sports, especially cricket, tennis, MMA, and boxing. [See Full Bio](https://www.selecthub.com/author/akshay-parekh/) [ ](https://www.selecthub.com/author/kim-oshaughnessy/) Edited by [Kim O'Shaughnessy](https://www.selecthub.com/author/kim-oshaughnessy/) Content Editor Kim is a digital content editor, having edited and managed content for over 40 different software categories. She discovered her zeal for writing while earning her BA in Communications at the University of Michigan. Kim enjoys working on any project that offers a creative outlet, and you can often find her blogging about video games in her spare time. If someone manages to pry her away from the game controller, she also enjoys spending time with family and friends. [See Full Bio](https://www.selecthub.com/author/kim-oshaughnessy/) Dan GreenfieldMake Healthcare Data Governance a Top New Year’s Resolution * ‹ * › ### Conversation ![Avatar](https://secure.gravatar.com/avatar/281d3616cf761f3582c0d76c23517846?s=32&d=mm&r=g) Write a response [Cancel reply](https://www.selecthub.com/medical/practice-management-software-compliance/#respond) Your message Your name \* Your email \* Website Save my name, email, and website in this browser for the next time I comment. Δ [ Go to mobile version ](https://www.selecthub.com/medical/practice-management-software-compliance/?amp=1) **Tier 1:** Fully/moderately supported out-of-the-box allowing for quick and easy deployment. Fully or moderately supported out-of-the-box with industry-leading capabilities and is immediately available after installation without needing any add-ons, integrations, or custom development. **Tier 2:** Supported with workarounds or add-ons that may require additional costs. Not directly available in the software, but can be accomplished using other built-in features, workarounds, or add-ons/products from the vendor with or without any additional cost. **Tier 3:** Requires partner integrations or custom development that is often at an additional cost. Requires additional integrations, plugins, marketplace applications from a third-party vendor, or custom development using the APIs, libraries, extensions, and development framework supported by the software, with or without any additional cost. 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