[Home](https://www.selecthub.com/) \> [Medical Management](https://www.selecthub.com/category/medical/) \> [Clinical Decision Support Systems](https://www.selecthub.com/c/clinical-decision-support-systems/) \> [UpToDate](https://www.selecthub.com/p/clinical-decision-support-systems/uptodate/) \> UpToDate vs Epocrates # UpToDate vs Epocrates Last Updated: July 20th, 2026 Our analysts compared [UpToDate](https://www.selecthub.com/p/clinical-decision-support-systems/uptodate/) vs [Epocrates](https://www.selecthub.com/p/clinical-decision-support-systems/epocrates/) based on data from our 400+ point analysis of [Clinical Decision Support Systems](https://www.selecthub.com/c/clinical-decision-support-systems/), user reviews and our own crowdsourced data from our [free software selection platform](https://www.selecthub.com/about/start-free-selection-project-site/?category=Clinical Decision Support Systems&cta=clinical-decision-support-systems). [Overview](#product-overview) [Pricing](#product-pricing) [Our Review](#product-analyst-summary) [User Ratings](#user-sentiment-section) [Features](#product-benefits-features) [Screenshots](#product-screenshots) Remove Add to Compare [![UpToDate Software Tool](https://cdn.selecthub.com/products/110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25/resources/normal/logo.png?1747751450)](https://www.selecthub.com/p/clinical-decision-support-systems/uptodate/) [ ![Product Awards](https://www.selecthub.com/display/images/awards_badge.svg) ](#awards-section) Remove Add to Compare [![Epocrates Software Tool](https://cdn.selecthub.com/products/8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38/resources/normal/logo.png?1747752380)](https://www.selecthub.com/p/clinical-decision-support-systems/epocrates/) [ ![Product Awards](https://www.selecthub.com/display/images/awards_badge.svg) ](#awards-section) [Get Free Demo](https://pmo.selecthub.com/get-product-demo/?category=Clinical+Decision+Support+Systems&product%5Fname=UpToDate&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25%2Fresources%2Fnormal%2Flogo.png%3F1747751450) [Demo](https://pmo.selecthub.com/get-product-demo/?category=Clinical+Decision+Support+Systems&product%5Fname=UpToDate&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25%2Fresources%2Fnormal%2Flogo.png%3F1747751450) [Request Pricing](https://pmo.selecthub.com/get-product-pricing-medical/?category=Clinical+Decision+Support+Systems&product%5Fname=UpToDate&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25%2Fresources%2Fnormal%2Flogo.png%3F1747751450&price=2) [Pricing](https://pmo.selecthub.com/get-product-pricing-medical/?category=Clinical+Decision+Support+Systems&product%5Fname=UpToDate&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25%2Fresources%2Fnormal%2Flogo.png%3F1747751450&price=2) [Get Free Demo](https://pmo.selecthub.com/get-product-demo/?category=Clinical+Decision+Support+Systems&product%5Fname=Epocrates&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38%2Fresources%2Fnormal%2Flogo.png%3F1747752380) [Demo](https://pmo.selecthub.com/get-product-demo/?category=Clinical+Decision+Support+Systems&product%5Fname=Epocrates&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38%2Fresources%2Fnormal%2Flogo.png%3F1747752380) [Request Pricing](https://pmo.selecthub.com/get-product-pricing-medical/?category=Clinical+Decision+Support+Systems&product%5Fname=Epocrates&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38%2Fresources%2Fnormal%2Flogo.png%3F1747752380&price=3) [Pricing](https://pmo.selecthub.com/get-product-pricing-medical/?category=Clinical+Decision+Support+Systems&product%5Fname=Epocrates&product%5Flogo=https%3A%2F%2Fd3uimxdj41cg3o.cloudfront.net%2Fproducts%2F8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38%2Fresources%2Fnormal%2Flogo.png%3F1747752380&price=3) ### Products Insights Product Ranking ## #1 among all Clinical Decision Support Systems ## #3 among all Clinical Decision Support Systems [Find out who the leaders are](https://pmo.selecthub.com/request-custom-scorecard?post%5Ftype=auto%5Fvs%5Farticle&category%5Fslug=clinical-decision-support-systems&product%5Fslug=uptodate&category=Clinical+Decision+Support+Systems) Price Starts From $60 Monthly [Free Trial is available →](https://pmo.selecthub.com/free-trial/?product%5Fname=UpToDate&category=Clinical Decision Support Systems&product%5Flogo=https://d3uimxdj41cg3o.cloudfront.net/products/110a186a520a14d6ecab41ff9c083741-bcfd53c1402364a82f97e036e3c7eb25/resources/normal/logo.png?1747751450) $179.99 Annually [Free Trial is available →](https://pmo.selecthub.com/free-trial/?product%5Fname=Epocrates&category=Clinical Decision Support Systems&product%5Flogo=https://d3uimxdj41cg3o.cloudfront.net/products/8ce241e1ed84937ee48322b170b9b18c-d8d7506f77356bb4e5e7dc235f584d38/resources/normal/logo.png?1747752380) Pros What we like about UpToDate and Epocrates: * Covers a wide range of specialties with deep, evidence-based clinical content for diagnosis and treatment. * Continuous updates from a large team of physician authors keep guidance current. * Includes patient education materials in multiple languages to share during visits. * Connects with EHR systems so you can pull guidance directly from patient records. * Strong drug database covering prescription, OTC, and alternative medicines for prescribing decisions. * Drug interaction checker lets you screen multiple medications at once for safety. * Users find the interface intuitive and quick to navigate at the point of care. * Offline access keeps core information available when connectivity is unreliable. Cons What we dislike about UpToDate and Epocrates: * Users report ongoing issues with the mobile app, including reliability and offline access problems. * Mobile app lacks basic features like text highlighting and note-taking that users want on the go. * Some users find the interface less user-friendly than expected and want better navigation. * Pricing isn't published, so you need to contact sales for a quote. * Users say the paid Epocrates Plus tier carries a high subscription cost. * Mobile app can be slow to start up, which frustrates users in fast-paced settings. * Pharmacists report inconsistencies between the mobile app and web version for drug formulation details. * Primarily available in English, which limits use in multilingual care settings. ### Our Review **Bottom line:** UpToDate and Epocrates both help clinicians make decisions at the point of care, but they fit different jobs. Pick UpToDate if you want deep, evidence-based guidance across many specialties. Pick Epocrates if your day revolves around quick drug lookups and interaction checks. UpToDate covers over 25 specialties with topics written and reviewed by a large team of physician authors. It's a strong fit if you're a doctor, resident, or medical student who needs to read up on a condition, weigh treatment options, or check the latest guidelines. The web platform is where it shines. Epocrates leans into drug information. The drug interaction checker, pill identifier, and formulary lookups are the core draw for physicians, nurses, and pharmacists who need fast answers about medications. It's less about reading long topic reviews and more about getting a quick, reliable answer between patients. On price, UpToDate starts at $60 per month and Epocrates starts at $179.99 per year. The billing intervals differ, so think about how each one maps to your budget and how often you'll actually use it. Epocrates also has a free tier with ads, while the paid Plus version unlocks more features. Both products have mobile app complaints. UpToDate users want highlighting and note-taking. Epocrates users see slow startups and gaps between the app and web version. If mobile access is your main use case, test both before you commit. For broad clinical reasoning across specialties, UpToDate is the stronger pick. For drug-focused work where speed matters more than depth, Epocrates fits better. Pharmacists who need detailed formulation data may find the Epocrates app limiting and should lean on its web version. ### User Sentiment Summary UpToDate has a user sentiment rating of 96 based on 3 reviews. Epocrates has a user sentiment rating of 91 based on 81 reviews. ![Excellent User Sentiment](https://www.selecthub.com/display/images/scores/excellent.svg) 3 reviews ![Excellent User Sentiment](https://www.selecthub.com/display/images/scores/excellent.svg) 81 reviews Synopsis Evaluating all review platforms, our market analysts have compiled the following user sentiment data. 96% of users recommend this product UpToDate has a 'excellent' User Satisfaction Rating of 96% when considering 3 user reviews from 1 recognized software review sites. 91% of users recommend this product Epocrates has a 'excellent' User Satisfaction Rating of 91% when considering 81 user reviews from 1 recognized software review sites. User Review Scores **Software Advice, Inc** n/a **4.57** (81) **TrustRadius** **4.8** (3) n/a ### Awards SelectHub awards earned by these products based on a comprehensive analysis by our research analysts. UpToDate stands above the rest by achieving an ‘Excellent’ rating as a User Favorite. ![User Favorite Award]() Epocrates stands above the rest by achieving an ‘Excellent’ rating as a User Favorite. ![User Favorite Award]() ### Product Assistance Training Resources Documentation In Person Live Online Videos Webinars Documentation In Person Live Online Videos Webinars Support Email Phone Chat FAQ Forum Knowledge Base 24/7 Live Support Email Phone Chat FAQ Forum Knowledge Base 24/7 Live Support ### Product Basics Company Size i Small Medium Large Small Medium Large Platforms Supported Windows Mac Linux Android Chromebook Windows Mac Linux Android Chromebook Deployment Supported Cloud On-Premise Mobile Cloud On-Premise Mobile Comparison of Top Alternatives [UpToDate Alternatives ](https://www.selecthub.com/clinical-decision-support-systems/uptodate/alternatives/) [Epocrates Alternatives ](https://www.selecthub.com/clinical-decision-support-systems/epocrates/alternatives/) ### Screenshots ![Screenshots]()![Screenshots]() ![Screenshots]()![Screenshots]() ### Key Features * **Clinical Topics** – Offers over 12,000 topics across more than 25 specialties so you can read up on conditions and treatments in depth. * **EHR Integration** – Connects with electronic health records so you can pull guidance directly from a patient's chart. * **Medical Calculators** – Includes more than 160 calculators for risk scores, dosing, and other bedside math. * **Practice Changing Updates** – Flags significant new evidence that may shift how you treat patients. * **Clinical Pathways** – Walks you through complex decisions step by step to keep care consistent. * **Drug Monographs** – Provides dosing, contraindications, and adverse reactions in a format built for fast lookup at the point of care. * **EHR Integration** – Works with electronic health records to cut redundant documentation and keep drug data close at hand. * **Medical Calculators** – Covers BMI, GFR, and other common calculations to speed up patient assessments. * **Drug Interaction Checker** – Lets you enter several medications at once to spot risky combinations before you prescribe. * **Pill Identifier** – Helps you identify unknown pills by shape, color, and imprint when patients bring in loose tablets. ### Top Alternatives in Clinical Decision Support Systems [ AgileMD ](https://www.selecthub.com/p/clinical-decision-support-systems/agilemd/) [ Andor ](https://www.selecthub.com/p/clinical-decision-support-systems/andor-health/) [ Avo ](https://www.selecthub.com/p/clinical-decision-support-systems/avomd/) [ Epocrates ](https://www.selecthub.com/p/clinical-decision-support-systems/epocrates/) [ EvidenceCare ](https://www.selecthub.com/p/clinical-decision-support-systems/evidencecare/) [ Micromedex ](https://www.selecthub.com/p/clinical-decision-support-systems/micromedex/) [ PeriGen ](https://www.selecthub.com/p/clinical-decision-support-systems/perigen/) [ ReferralMD ](https://www.selecthub.com/p/clinical-decision-support-systems/referralmd/) [ SOAP Health ](https://www.selecthub.com/p/clinical-decision-support-systems/soap-health/) [ VirtuAlly ](https://www.selecthub.com/p/clinical-decision-support-systems/virtually-io/) ### Head-to-Head Comparison ![UpToDate Software Tool]() ![AgileMD Software Tool]() [UpToDate VS AgileMD](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-agilemd/) ![UpToDate Software Tool]() ![Andor Software Tool]() [UpToDate VS Andor](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-andor-health/) ![UpToDate Software Tool]() ![Avo Software Tool]() [UpToDate VS Avo](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-avomd/) ![UpToDate Software Tool]() ![Epocrates Software Tool]() [UpToDate VS Epocrates](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-epocrates/) ![UpToDate Software Tool]() ![Micromedex Software Tool]() [UpToDate VS Micromedex](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-micromedex/) ![UpToDate Software Tool]() ![PeriGen Software Tool]() [UpToDate VS PeriGen](https://www.selecthub.com/clinical-decision-support-systems/uptodate-vs-perigen/) **About SelectHub (and our data)** We’re the employee-owned Austin-based startup democratizing software data so you can make your decisions in an influence-free zone. Our market data is crowdsourced from our user-base of 100,000+ companies. WE DISTILL IT INTO REAL REQUIREMENTS, COMPARISON REPORTS, PRICE GUIDES and more... ![SelectHub Products Reporting and Analytics]() ![SelectHub Products Cost and Pricing Guide]() **Tier 1:** Fully/moderately supported out-of-the-box allowing for quick and easy deployment. Fully or moderately supported out-of-the-box with industry-leading capabilities and is immediately available after installation without needing any add-ons, integrations, or custom development. **Tier 2:** Supported with workarounds or add-ons that may require additional costs. Not directly available in the software, but can be accomplished using other built-in features, workarounds, or add-ons/products from the vendor with or without any additional cost. **Tier 3:** Requires partner integrations or custom development that is often at an additional cost. Requires additional integrations, plugins, marketplace applications from a third-party vendor, or custom development using the APIs, libraries, extensions, and development framework supported by the software, with or without any additional cost. [Close](#) ```json { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.selecthub.com/" }, { "@type": "ListItem", "position": 2, "name": "Medical Management", "item": "https://www.selecthub.com/category/medical/" }, { "@type": "ListItem", "position": 3, "name": "Clinical Decision Support Systems", "item": "https://www.selecthub.com/c/clinical-decision-support-systems/" }, { "@type": "ListItem", "position": 4, "name": "UpToDate", "item": "https://www.selecthub.com/p/clinical-decision-support-systems/uptodate/" }, { "@type": "ListItem", "position": 5, "name": "UpToDate Vs Epocrates" } ] } ```